You can find the detailed information for Outlook 2016, 2013, 2010, 2007 and older versions here: How to disable Outlook add-ins.This problem is most typical for Office 365/Office 2016/Office 2013 but it may occur in Outlook 2010 and lower versions too.The main symptom is Outlook hanging on the Loading Profile screen, and the main cause is a conflict between the operating system and OEM video drivers.

Try to open Outlook and if it starts without errors, congratulations!

You do not need the remainder of this article : ) Or maybe, it's worth to bookmark it for the future.

The entire text of the error message is this: " Start Outlook and the error should be gone.

If you work in a corporate environment and your company uses an Outlook Exchange server, then the "unable to open Outlook" problem may be caused by something known as Cached Exchange Mode.

A good indication that the file is corrupted is when its size is 0 KB.

No one knows the exact reason why this happens, but all versions of Microsoft Outlook from 2003 to the newest Outlook 2016 may be affected.

These solutions address less common errors that may occur in certain scenarios.

As the error description explains, this error happens if you have a corrupted or outdated MAPI32. Usually this happens when you'd installed a newer version of Microsoft Office and then installed an older one.

I cannot recommend any particular tool because luckily have never had to use any on my own machine.

Starting Outlook in Safe Mode actually means that it will be run without any add-ins that are currently installed on your machine.

A few articles ago we discussed what can be done when Outlook is freezing and not responding.